Megaloblastic anemia following the use of primidone.
نویسندگان
چکیده
HILE the umsderhyimmg causes of the nsajority of misegaloblast-ic amsemssias are usow knsown, the list is usotyet exhaustive amid it has recemstly been suggested that amsticomsvulsammt drutgs nsay commstitute a mies ’ etiohogic fact-or its sonic cases. The postulated effectof these drutgs is particutlarly strikimsg ins that megaloblastic ausemia is msot seems wit-h the niomispecific toxic agcmmts such as may cause, for iumstaumce, aplastic amsemia. It is true that they bear a slight chemuuicah resensblams (‘C t 0 folic a(i(l
منابع مشابه
Megaloblastic anemia from methophenobarbital.
By R. J. CALVERT, E. HUnwoilTil AND A. L. MACBEAN I HE OCCASIONAL DEVELOPMENT of megaloblastic anemia during the administration for months or years of certain anticonvubsant drumgs ( phenytom sodium and/or primidone, with or withoumt phenobarbital ) has been reviewed by Gydell#{176} and Newman and Sumner.11 Ouir report concerns an epileptic patient who presented as a gynecologic emergency with ...
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DAWSON, D. W., and JOHNSON, J. (1958): Anticonvulsants and Megaloblastic Anaemia, Brit. med. J., i, 397. GIRDWOOD, R. H., and LENMAN, J. A. R. (1956): Anaemia occurring During Primidone Therapy, Brit. med. J., i, 146. GOUGH, K., READ, A., MCCARTHY, C., and WATERS, A. (1963): Megaloblastic Anaemia due to Nutritional Deficiency of Folic Acid, Quart. J. Med. N.S., 32, 243. HAWKINS, C. F., and MEYN...
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Repeated bone marrow examination was found to be of value in assessing response to treatment in megaloblastic anemia. The objective of this study was monitoring the response of megaloblastics to treatment, concerning the location of neutrophilic myeloperoxidase and myeloperoxidase index (MPXI) and their variation in megaloblastic erythroid progeny. It is possible to follow up megaloblastic ...
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ansemia, was caused by the barbiturates she was taking. Both amylobarbitone sodium and quinalbarbitone sodium, the constituents of tuinal, are closely related chemically to primidone, sodium phenytoin, and phenobarbitone, but a megaloblastic anaemia has not previously been described in association --ith their use. The doses that this patient was taking (gr. 18-20 for 6-8 months) were, however, ...
متن کاملPyrexia in a Patient with Megaloblastic Anemia: A Case Report and Literature Review
Deficiency of vitamin B12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. We aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin B12 and folate deficiency. The pyrexia subsided following the intramuscular injection of vitamin B12 and oral folic acid a...
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ورودعنوان ژورنال:
- Blood
دوره 12 2 شماره
صفحات -
تاریخ انتشار 1957